Anti Cancer Tablet

This medication is used to treat breast cancer in women who have gone through "the change of life". Anastrozole works by lowering estrogen hormone levels to help shrink tumors and slow their growth. Take this medication by mouth with or without food, usually once a day, or as directed by your doctor. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. Do not increase your dose or take this medication more often without your doctor's approval

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Being a client-centric organization, we are engaged in offering a distinct collection of Melphalan Tablet.

Application:

• Used to treat cancer

Features:

• Precise composition
• Hygienically processed
• Long shelf life

Description:

Melphalan is a bifunctional alkylating agent which is active against selective human neoplastic diseases. Melphalan is a bifunctional alkylating agent. Formation of carbonium intermediates from each of the two bis-2-chloroethyl groups enables alkylation through covalent bonding with the 7-nitrogen of guanine on DNA, cross-linking two DNA strands and thereby preventing cell replication.

Melphalan is also known as a D 'Isomer',It is less active against certain animal tumours, and the dose needed to produce effects on chromosomes is larger than that required with the L-isomer. Melphalan is practically insoluble in water and has a pKa1 of ~2.5.

How melphalan works:

• Melphalan tablet is one of a group of drugs called alkylation agents
• It sticks to one of the cancer cell's DNA strands
• DNA is the genetic code that is in the nucleus of all animal and plant cells
• The cell cannot then grow and divide into 2 new cells

How to use melphalan:

• Melphalan is a clear liquid that you have as a drip (intravenous infusion)
• You may have it through a short tube put into a vein in your arm each time you have treatment
• These are long, plastic tubes that give the drug directly into a large vein in your chest
• You have the tube put in just before your course of treatment starts and it stays in place as long as you need it

These side effects are less common side effects:

• Allergic reaction
• Mouth sores
• Diarrheal
• Loss of fertility
• Hair loss

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Additional Information:

• Item Code: AKI-AC-701

In line with clients' variegated requirements, we bring forth a distinguished collection of the Erlotinib Tablet.

Application:

• Used to treat non-small cell lung cancer.

Features:

• Highly effective
• Safe to use
• Accurate composition

Description:

Erlotinib is an epidermal growth factor receptor/human epidermal growth factor receptor type 1 tyrosine kinase inhibitor. Erlotinib tablet potently inhibits the intracellular phosphorylation of EGFR. EGFR is expressed on the cell surface of normal cells and cancer cells.

The potent effectiveness of Erlotinib in blocking EGFR-mediated signalling in these EGFR mutation positive tumours is attributed to the tight binding of Erlotinib to the ATP-binding site in the mutated kinase domain of the EGFR.

Due to the blocking of downstream-signalling, the proliferation of cells is stopped, and cell death is induced through the intrinsic apoptotic pathway.

Tumour regression is observed in mouse models of enforced expression of these EGFR activating mutations.

Erlotinib dosing information

• Usual Adult Dose for Non-Small Cell Lung Cancer: 150 mg orally once a day
• Duration of therapy: Until disease progression or unacceptable toxicity

Uses:

First-line treatment of patient with metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations

Maintenance treatment of patient with locally advanced or metastatic NSCLC whose disease has not progressed after four cycle of platinum-based first-line chemotherapy.

Erlotinib tablets side effects:

Get emergency medical help if you have any signs of an allergic reaction to Erlotinib: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Do not use Erlotinib at once if you have:

• Sudden chest pain
• Discomfort
• Wheezing
• Dry cough
• Feeling short of breath

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Additional Information:

• Item Code: AKI-AC-702

Product Details:

We feel immensely pleased to offer an exclusive gamut of Gefitinib Tablet.

Application:

• Used to treat lung cancer.

Features:

• Safe to use
• Purity
• pH balanced

Description:

Gefitinib is a selective small molecule inhibitor of the epidermal growth factor receptor tyrosine kinase and is an effective treatment for patients with tumours with activating mutations of the EGFR tyrosine kinase domain regardless of line of therapy. This drug used for the treatment of locally advanced or metastatic non-small cell lung cancer, after failure of both platinum-based and taxane-based chemotherapies.

Gefitinib 250mg Tablets is manufactured by Natco Pharma India and contains the drug Gefitinib I.P 250 mg in each tablet that is a targeted therapy. Gefitinib Tablets which classified as a signal transduction inhibitor. Gefitinib I.p 250mg inhibits EGFR tyrosine kinase by binding to the triphosphate (ATP)-binding site of the enzyme.

Mechanism of action and pharmacodynamic effects:

The epidermal growth factor and its receptor have been identified as key drivers in the process of cell growth and proliferation for normal and cancer cells.EGFR activating mutation within a cancer cell is an important factor in promotion of tumour cell growth, blocking of apoptosis, increasing the production of angiogenic factors and facilitating the processes of metastasis.

No clinically relevant activity has been shown in patients with known EGFR mutation-negative tumours.

Drug class and mechanism:

Gefitinib tablet is a drug that is used to treat several types of lung cancer. It works by preventing lung cancer cells from growing and multiplying.

Many cells, including cancer cells, have receptors on their surfaces for epidermal growth factor (EGF), a protein that is normally produced by the body and that promote s the growth and multiplication of cells.

When EGF attaches to epidermal growth factor receptors (EGFRs), it causes an enzyme called tyrosine kinas to become active within the cells.

Tyrosine kinase triggers chemical processes that cause the cells, including cancer cells, to grow, multiply, and spread.

Gefitinib attaches to EGFRs and thereby blocks the attachment of EGF and the activation of tyrosine kinas. This mechanism for stopping cancer cells from growing and multiplying is very different from the mechanisms of chemotherapy and hormonal therapy. Gefitinib was approved by the FDA in May 2003.

Uses of Gefitinib Tablets:

Gefitinib is prescribed to treat lung cancer. It is proven to help to slow down cancerous cells growth and reproduction. It works by blocking a certain protein enzyme called tyrosine kinase.

Dosage and Administration:

Most patients who have been prescribed Gefitinib tablets are told to dose once a day, with or without food. Unless otherwise instruct by your physician, tablets should always be swallowed whole and should not be chewed, crushed or dissolved in liquid.

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Additional Information:

• Item Code: AKI-AC-703

Product Desciption :

Imatinib tablet treats some cancers and certain blood diseases. It is a chemotherapy drug that works by slowing or preventing the growth of most cancers cells. It is given to patient suffering from leukaemia, a bone marrow cancer.

Imatinib medication should be taken with meal and full glass of water as directed by doctor. You can dissolve the capsules in a glass of water or apple juice. Stir the combination properly until the pills dissolve, and drink right away. You should stop eating grapefruit or drinking grapefruit juice as directed by your medical doctor. Grapefruit can increase the threat of side results with this drug.

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Product Details:

Product Desciption :

Anastrozole tablets contain a substance called Anastrozole. This belongs to a group of medicines called aromatase inhibitors. This medication is used to treat breast cancer in women who have gone through the change of life. Treating certain types of breast cancer in a woman who has been through menopause, including women with disease progression after Tamoxifen therapy. Anastrozole tablets mostly used in dose of 1mg and it is prescribed for hormone receptor-positive, early breast cancer in postmenopausal women as adjuvant treatment.

Do not try anastrozole tablets if you are pregnant or planning to become pregnant or are breast-feeding.

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Product Details:

Product Desciption :

Tamoxifen is in a class of medicine known as ant estrogens. Generic Tamoxifen tablet blocks the activity of estrogens in the breast. This may stop the growth of some breast tumours that need estrogens to grow. Tamoxifen ingredient medicine is used to reduce the risk of breast cancer in women who are at high risk for the disease due to their age, personal medical history, and family medical history. it treats breast cancer in men and women. Tamoxifen cannot be used by pregnant women it could harm the unborn baby.

Tamoxifen comes in form of tablets taken by mouth, once or twice a day with or without food.

 

The following side effects are common (occurring in greater than 30%) for patients taking Tamoxifen:

Loss of libido (particularly in men) (see )

Swelling (fluid retention in feet, ankles, or hands)

Menstrual irregularities

Vaginal bleeding

Weight loss

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